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G. Wang



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    P3.02 - Poster Session/ Treatment of Localized Disease – NSCLC (ID 211)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Treatment of Localized Disease - NSCLC
    • Presentations: 1
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      P3.02-014 - COPD Being Misdiagnosed in Lung Cancer Patients with Thoracic Operation (ID 303)

      09:30 - 09:30  |  Author(s): G. Wang

      • Abstract

      Background:
      Chronic obstructive pulmonary disease (COPD) is a risk factor and important coexisting disease for lung cancer; at the same time, coexisting COPD owes unfavorable effect on management of lung cancer. However, the current status of management of COPD in lung cancer patients with operable sites is not fully described. This study addressed this issue in a general teaching hospital in China.

      Methods:
      All patients with lung cancer underwent surgery were collected retrospectively from Jan. 2002 to Dec. 2008. Medical records were reviewed about clinical information, pathological records, lung functions, etc., so as to analysis comorbidity rate about COPD and characters. The definition of COPD was according the spirometric criteria of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) document. The diagnostic rate (COPD recorded as a discharge diagnosis/spirometry-defined percentage) and conformity to GOLD treatment guidelines were investigated. The factors influencing diagnosis were analyzed.

      Results:
      Among all 437 undergone surgery patients aged older than 40 years old, 94 patients were diagnosed COPD, the prevalence of COPD was 21.36%(41 as GOLD 1, 52 as GOLD 2, and 1 as GOLD 3)。Among them, 89.36% was male, with average age being 63.3 years old. Only 9 patients were diagnosed as COPD, the rate of misdiagnosis was 90.4% and all of them did not receive pulmonary function test. 71.3% of those patients with COPD had smoke history; average smoke intensity was 26.7 pack-year. All surgery of pathological staging were classified as followed according to the standards of the Union International Contre le Cancer (UICC):Ⅰstage (A+B:38+119); Ⅱ(A+B:14+83); Ⅲ(A+B:100+32); IV: 31; No specific: 20 cases. And patients complicated with COPD presented stages as followed:Ⅰstages (A+B:6+23)、Ⅱ(B:21); Ⅲ(A+B:33+7); IV: 1; No specific: 3 cases. The rate of lung cancer complicated with COPD was 24.8%, 21.6%, 30.3% respectively.

      Conclusion:
      Patients of lung cancer undergone surgery have high risk morbidity of COPD. To improve the result of peri-operation period management, COPD should be pay attention to treat for these patients.