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J.H. Chang



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    P2.11 - Poster Session/ Palliative and Supportive Care (ID 230)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Palliative and Supportive Care
    • Presentations: 1
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      P2.11-015 - Factors Related with Reluctance to Treatment in Lung Cancer (ID 1032)

      09:30 - 09:30  |  Author(s): J.H. Chang

      • Abstract
      • Slides

      Background:
      Lung cancer is one of increasing cancer in incidence with longer survival of life in Korea. Some patients do not have a condition to receive cancer therapy by the decision of patients themselves and/or family as well as doctors. Refusal or avoidance of active treatment is prone to suffer from cancer symptoms and causes to shorten life survival. The purpose of this study is to define factors related to avoid or refuse active therapy in lung cancer.

      Methods:
      The population was retrospectively collected from patients’ record in one tertiary university hospital from 2010 to 2012. Total 306 subjects were enrolled as lung cancer and 18 subjects were excluded due to incomplete data or follow-up loss. Among 288 subjects, 66 subjects, avoiding cancer treatment were allocated to nontreatment group (NTG), whereas remaining 222 subjects to treatment group (TG).

      Results:
      Mean age of NTG was older than TG. Previous operation history, low BMI, high ECOG score and Charlson comorbidity index (CCI) score were significant in NTG. Factors of sex, smoking behavior, drinking, offspring number, degree of scholarship, familial history of cancer, pathologic type, TNM stage, presence of chest symptoms or systemic symptoms, and absence of occupation, religion and partner were insignificant. In univariate and multivariate analysis, high ECOG (2-3 vs 0-1; odds ratio [OR]: 6.0; 95% confidence interval [CI]:1.5-23.4) and high CCI score (OR: 1.3; 95% CI; 1.02-1.7) were the significant determinants to the avoidance of treatment.

      Conclusion:
      Nontreatment decision in lung cancer was associated with performance status and comorbidities, which are considered prior to the guidance of cancer treatment. Patient's personal factors give little influence to the decision of cancer treatment.

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