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A. Csanadi
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P2.08 - Poster Session/ Thymoma, Mesothelioma and Other Thoracic Malignancies (ID 225)
- Event: WCLC 2015
- Type: Poster
- Track: Thymoma, Mesothelioma and Other Thoracic Malignancies
- Presentations: 1
- Moderators:
- Coordinates: 9/08/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)
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P2.08-018 - The Impact of the Resection Margin on Recurrence and Survival in Bronchopulmonary Carcinoids (ID 2411)
09:30 - 09:30 | Author(s): A. Csanadi
- Abstract
Background:
Complete surgical resection is the treatment of choice in bronchopulmonary carcinoids. Previously published data showed no inferiority of sublobar versus lobar resection. Data on the extent of resection margins are lacking, thus we aimed to analyze resection margins in pulmonary carcinoids and correlated them with survival and recurrence.
Methods:
We retrospectively analyzed 85 patients that underwent surgery for atypical (AC) or typical (TC) pulmonary carcinoids. Patient charts were reviewed and clinicopathologic and survival data was collected. Pathology reports were reviewed for length of resection margins.
Results:
The median follow-up period was 42.3 months (range 0.3 - 172.2). There was no statistically significant difference in disease-free survival (DS) when comparing resection margins ≤2 mm to >2 mm (p=0.93, Hazard Ratio (HR)=1.7). When looking at AC alone, a worse DS can be seen if the resection margin was smaller than 2 mm (p=0.06, HR=15.8). In AC likelihood of recurrence was higher when the resection margin was ≤1 cm (Odds ratio=5.1, p=0.28). In TC this tendency was not present (Odds ratio=1.2, p=1).
Conclusion:
There is a trend towards a worse prognosis and higher likelihood of recurrence in smaller resection margins in AC in contrast to TC. Due to low sample size no definitive statements can be made based on this study, however respective data on these rare tumors cannot be drawn from tumor databases. The resection margin is the most critical issue for the treating surgeon and any information on this topic is of highest importance to the field.
