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H. Marushima
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P2.03 - Poster Session/ Treatment of Locoregional Disease – NSCLC (ID 213)
- Event: WCLC 2015
- Type: Poster
- Track: Treatment of Locoregional Disease – NSCLC
- Presentations: 1
- Moderators:
- Coordinates: 9/08/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)
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P2.03-009 - Single Institutional Experience of the Surgical Treatment of Second Primary Lung Cancer (ID 2283)
09:30 - 09:30 | Author(s): H. Marushima
- Abstract
Background:
Surgical strategies for second primary lung cancer is still a controversial issue. We sought to assess postoperative and survival outcome of surgical resection in the treatment of patients with a second primary lung cancer.
Methods:
From January 2010 to August 2014, 439 patients with lung cancer were underwent surgical resection at our institution. Among them, 18 (4.1%) patients with second primary lung cancer, classified by the criteria proposed by Martini and Melamed, were treated. We retrospectively reviewed these cases for assessment of treatment outcome.
Results:
There are 12 males and 6 females with mean (range) age of 72 (58-85). We had 9 (50%) patients with a synchronous tumor and 9 (50%) with metachronous. Median interval time (range) between metachronous tumors was 42 months (1-194). These second primary located with 9 (50%) cases in right and 9 (50%) cases in left side. Mean (range) tumor size was 20 (7-45) mm with ground glass opacity in 9 (50%) cases. Histology was adenocarcinoma in 15 (83%), large cells in 2 (11%), and small cells in 1 (6%). Pathological stage was IA in 11 (61%), IB in 4 (22%), and IIA in 3 (17%). Mean VC and FEV1.0 were 2.48L and 1.8L, respectively. As second treatment, we performed 3 (17%) lobectomies, 4 (22%) segmentectomies and 11 (61%) wedge resections. Mean operation time and blood loss was 133 min and 47 ml, respectively. Major postoperative complications at second treatment were prolonged air leakage in 2 (11%) cases and interstitial pneumonitis in 1 (5%) case. Operative morbidity and mortality were 16% and 5%, respectively. There years overall survival were 94% with 13 months of median follow up time. Loco-regional and distant recurrence were occurred in 2 (12%) and 1 (5%) cases, respectively.
Conclusion:
From our experience, surgical treatment of second primary lung cancer is feasible. Surgical strategies including lobectomy, segmentectomy, and wedge resection should be selected with considering in the balance with oncological and pulmonary functional status. Furthermore cases need to be collected for detail analysis.
