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N. Spizzamiglio
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P1.04 - Poster Session/ Biology, Pathology, and Molecular Testing (ID 233)
- Event: WCLC 2015
- Type: Poster
- Track: Biology, Pathology, and Molecular Testing
- Presentations: 1
- Moderators:
- Coordinates: 9/07/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)
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P1.04-096 - Second Tumors in Lung Cancer (LC) Patients. Should We Think About This Issue in Long Term Survival Setting? (ID 1594)
09:30 - 09:30 | Author(s): N. Spizzamiglio
- Abstract
Background:
Lung cancer (LC) is the first cause of cancer death in men and the third in women in Argentina. Multiple studies have shown that patients with LC treatment prolong their survival and thus increases the risk of second tumors. The prevalence of second tumors after lung cancer ranges from 2% to 15%, which further increases after ten years since the diagnosis was made. Reports from latinoamerica are scarce.
Methods:
We evaluated retrospectively the medical record of pts with LC from 2005 to 2014. We recorded the presence of second tumor in the follow-up.
Results:
Two hundred twelve patients were registered. Ten patients (4.56%) were recorded with second tumors. Median age was 68 years old (r. 59-80),most of them were men (80%) and smokers (90%). Regarding primary tumor, 90% (9 pts) were non small lung cancer (NSCLC) versus 10% SCLC. The most frequent histological type was squamous carcinoma 60% (6 pts) and adenocarcinoma 30% (3 pts). The most frequent second tumor site was: lung 40% (4 pts) followed by larynx , bladder, kidney, ovary, breast and NHL. Median survival was 22 months (r. 1-160) in pts without second tumors versus 65 months (r. 22-165) in pts with second tumors (p: 0,005 – Fisher Test). The median of diagnosis time of second tumor was 22.5 months.
Conclusion:
These results show the paramount importance of a correct follow-up in these patients. In our series, one each twenty patients with lung cáncer had a second cancer during their follow-up. The most frequent site were respiratory and genitourinary tracts. There was a significant difference in the survival in pts with second tumors.
