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J. He
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P1.04 - Poster Session/ Biology, Pathology, and Molecular Testing (ID 233)
- Event: WCLC 2015
- Type: Poster
- Track: Biology, Pathology, and Molecular Testing
- Presentations: 1
- Moderators:
- Coordinates: 9/07/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)
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P1.04-017 - Pulmonary Lymphoepithelial-Like Carcinoma: A Surveillance, Epidemiology, and End Results Database Analysis (ID 2660)
09:30 - 09:30 | Author(s): J. He
- Abstract
Background:
Pulmonary lymphoepithelial-like carcinoma (LELC) is one of the rare histological non-small cell lung cancers. Only a few case reports have been published. The knowledge of its characteristics and prognosis is limited. Based on the data of the Surveillance, Epidemiology, and End Results Database (SEER), an analysis was performed to fill the gap of our knowledge
Methods:
Characteristics, treatment and outcomes of all pulmonary LELC patients was extracted both from the SEER database with 18 registered center from 1973-2011 using SEER*Stat 8.1.5 Statistical analysis was performed using SPSS 16.0 and GraphPad Prism 5.
Results:
A total of 62 patients with pulmonary LELC are identified and recorded. Among them, Caucasian patients account for the largest proportion (64.4%). The medium age at diagnosis is 65. The 1, 3 and 5 years survival rates of LELC are 85.6%, 74.5% and 55.2%. The median survival time of all LELC patients is 34 months. Comparing to other types of lung cancer, LELC has a better survival. 14 patients have received radiation, while most of the early stage LELC patients (30/34, 88.2%) have received surgical resection as the first treatment.Figure 1
Conclusion:
Pulmonary LELC is a rare pathological type of lung cancer . In this cohort, male and Caucasian patients account for a large proportion of LELC patients. The mean age of pulmonary LELC patients in this study is older than the patients in Asian studies. A large amount of patients are in the early stages (localized and regional) when they are diagnosed as LELC. LELC has a better prognosis than adenocarcinoma, most early stage patients have received surgical resection. However, no prognosis factor has been identified in our study. In order to understand pulmonary LELC more thoroughly, more cases are required.
