Author of

• 13508

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  P1.02 - Poster Session/ Treatment of Localized Disease – NSCLC (ID 209)

  • Event: WCLC 2015
  • Type: Poster
  • Track: Treatment of Localized Disease - NSCLC
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/07/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)

  • 13520

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    P1.02-012 - Study for Prognostic Impact of Tumor Volume Instead of Tumor Size for T Staging in NSCLCancer (ID 1407)

    09:30 - 09:30  |  Author(s): D. Kim
    • Abstract

    Background:
    Size criteria have been used as a gold standard for a long time in cancer staging of all kinds of solid tumors. However, real tumor mass is usually neither spherical, nor symmetrical in shape. Therefore, single dimension length of tumor does not stand for the tumor volume exactly. We conducted the feasibility test of volume criteria for T staging.
    
    Methods:
    From April 1998 to April 2015, 425 lung tumor masses were resected. Among them, 187 masses of completely resected (R0) pT1a,1b,2a,2bN0M0 were enrolled for study. Their survival data were used for comparing log-rank statistics between size-based T(s) stage and volume-based T(v) stage. Tumor volumes were calculated from two-to-three dimension lengths of tumor from biopsy specimen.
    
    Results:
    Overall log-rank statistics was p=0.4377 and there was no detectable numerical order for trend among pT1a~pT2b in size-based T(s) stage. However, overall log-rank was p=0.1153 and log-rank for trend was p=0.0241 in volume-based T(v) stage. Cut-off values for volume T stage were selected as V1 (less than 2cc), V2 (more than 2cc and less than 4cc), V3 (more than 4cc and less than 9cc) and V4 (more than 9cc) from log-rank statistics.
    
    Conclusion:
    Volume-based T(v) stage shows better discrimination power comparing size-based T(s) stage in T1-2N0 NSCLCa.