Author of

• 12837

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  P3.22 - Poster Session 3 - Epidemiology, Etiology (ID 168)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Prevention & Epidemiology
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/30/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 12841

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    P3.22-004 - Cancer and Tuberculosis, experience in a Chest Hospital (ID 1952)

    09:30 - 09:30  |  Author(s): R. Billone
    • Abstract

    Background
    Cancer and tuberculosis are two conditions that can coexist, and their association is more common in areas of high prevalence of tuberculosis like developing countries.

    Methods
    To report the clinical characteristics of patients with cancer and tuberculosis association treated at a chest hospital. In this restrospective study, we reviewed the records of 970 patients treated for tuberculosis during the period 1998-2010.

    Results
    There were 16 patients with cancer and tuberculosis association. The average age was 55.25 years, 11 males and 5 females. Cancer was diagnosed before tuberculosis in 12 patients. The median time to onset of infection was 24 months. Tuberculosis preceded the cancer diagnosis in 3 patients and was obtained simultaneously by surgical biopsy in 2 cases. The most frequent association was with pulmonary cancer and hematological malignancies, 3 patients each. Pulmonary tuberculosis was present in 11 patients, 4 were extrapulmonary and 1 patient had both pulmonary and extrapulmonary disease. Bacteriological confirmation was obtained in 49% of patients and histopathology in 31.3%. Regarding to the evolution of tuberculosis, 50% completed treatment, 25% were derived, lost to follow up in 12.5% and 6.3% died during treatment of infection .

    Conclusion
    The probability of association of cancer and tuberculosis in the same patient should be taken into account in countries with high prevalence of tuberculosis. The coexistence of these two diseases frequently poses diagnostic difficulties and delay in treatment of both diseases. In countries with high rates of latent TB the oncologist should consider the possibility of reactivation of TB secondary to alterations of immunity produced by tumor and chemo or radiation treatments.