Virtual Library

 x 
My Library Virtual Library FAQ

Start Your Search

Y.S. Kim



Author of

  • +

    P3.19 - Poster Session 3 - Imaging (ID 181)

    • Event: WCLC 2013
    • Type: Poster Session
    • Track: Imaging, Staging & Screening
    • Presentations: 1
    • +

      P3.19-013 - The relationship between iodine-related attenuation of dual-energy CT and standardized uptake value of <sup>18</sup>FDG PET-CT in patients with non-small cell lung cancer (ID 2065)

      09:30 - 09:30  |  Author(s): Y.S. Kim

      • Abstract

      Background
      A recent study revealed that maximum iodine-related attenuation (IRA~max~) of dual-energy CT (DECT) of primary tumor strongly correlates with maximum standardized uptake value (SUV~max~) of [18]FDG PET-CT in non-small cell lung cancer (NSCLC) (n = 27; r = 0.785; p = 0.001). It suggested that DECT could serve as a valuable functional imaging test in NSCLC. The aim of our study is to validate the previous results in our NSCLC cohort.

      Methods
      Twenty-seven patients with NSCLC who underwent both DECT and [18]FDG PET-CT were analyzed. The maximum and mean IRA as well as virtual non-contrast (VNC) images were calculated from DECT. Pearson correlation test was used to analyze the relationship between all measurements of DECT and the SUV~max~ of [18]FDG PET-CT in primary tumors and lymph nodes.

      Results
      Twenty-seven primary tumors and 51 thoracic lymph nodes with an SUV~max~ of >2.5 were included in analyses. In primary tumors, there was a moderate correlation between IRA~max~ and SUV~max~ (r = 0.565; p = 0.002) whereas no correlation was found between other DECT measurements and SUV~max.~ In lymph nodes, we observed no correlation between IRA~max~ and SUV~max~ (r = 0.197; p = 0.165) as well as between other DECT measurements and SUV~max.~

      Conclusion
      In patients with NSCLC, correlation between IRA~max~ and SUV~max ~was observed in primary tumors but not in lymph nodes. Because of relatively small population in our study and previous study, further large prospective studies are needed for validation.