Author of

• 11692

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  P2.10 - Poster Session 2 - Chemotherapy (ID 207)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Medical Oncology
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/29/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 11734

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    P2.10-042 - Lung cancer among Swedish and imigrants. Incidens, histopathology, treatment and survival. (ID 2584)

    09:30 - 09:30  |  Author(s): H. Högberg
    • Abstract

    Background
    Lung cancer represents the leading cause of cancer-related death world wide. Several studies have shown that the risk of developing lung cancer is associated with socioeconomic status. Recently a Swedish study showed that socioeconomically disadvantaged groups with NSCLC receive less intensive care. Low education remained an independent predictor of poor survival only in women with early stage disease. Foreign-born people constitute 12.5% of the Swedish population in Sweden.

    Methods
    A retrospective analysis of all patients with lung cancer at the Department of Respiratory Medicine and Allergy, Karolinska University Hospital - Solna during 030101—061231. In all, 1353 cases of lung cancer were diagnosed in which 157 (11.6%) were immigrants. The mean age in Swedish patients was 69, median 70 and range 38-96 years. The figures for the immigrants was 65, 66 respectively 38-90 years.91,3% of the Swedish and 92,3% of the immigrant patients were either smoker or former smoker. There was no significant differences between the groups.

    Results
    In 105 (8,8%) Swedish and 7 (4,5%) of the immigrants the diagnosis was clinical Adenocarcinoma was the most common subtype found in both Swedish and immigrant patients 44,7% respectively 40,1%, squamous cell carcinoma 17,5% resp 21,7% and small cell lung cancer 12,2% respectively 14% . No significance differences between the groups.19,1% of the Swedish and 14% of the immigrants were diagnosed as stage I, 2,4% resp 4,4% as stage II, 7,9% resp 7% as stage IIIa and 70,4% resp 74,5% as stage IIIB/IV. Nearly 86% of the Swedish and 84,1% of the immigrants had PS 0-2 and 14,3% resp 15,9% had PS 3-4. Chemotherapy given to 387(32,4%) of the Swedish and 58(36,9%) of the immigrants, concomitant chemo-radiotherapy to 90(7,5%) resp 16(10,2%), radiotherapy against the tumor 8,4% resp 8,3%, SBRT to 2,7% resp 1,3%. Surgery were performed among 9,1% of the Swedish and 10,8% of the immigrants, 5,9% resp 4,5% given adjuvant chemotherapy. Approximately 20% of the Swedish and 15,9% of the immigrants given no therapy at all. There was no significant differences in treatment between the two groups p<0.551.The median survival time for the Swedish patients was 245 days and for other nationalities it was 269 days with no statistical significant difference. For Swedish female patients the median survival time was 273 days and for females from other nationalities it was 329 days with no significant difference.No significant differences in survival and staging between the swedish and the imigrants. There was no significant difference in survival between Swedish and non-Swedish patients within performance status groups.

    Conclusion
    In this study, we used cohort of patients with lung cancer (except carcinoid), with a focus on ethnicity, to determine whether racial/ethnic disparities exist in overall survival. Another objective of our analysis was to determine whether any differences in survival could be attributed to disease-associated variables. To our best knowledge no previous study has investigated the incidens of lung cancer in immigrants in Sweden. This study showed no significant difference in survival between immigrants and Swedish patients with lung cancer.