Author of

• 10643

  +

  P1.07 - Poster Session 1 - Surgery (ID 184)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/28/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 10673

    +

    P1.07-030 - Prognostic factors for patients in brain metastasis with no extracranial metastasis after resection of non-small cell lung cancer (ID 2149)

    09:30 - 09:30  |  Author(s): D.J. Kim
    • Abstract

    Background
    We investigated the prognostic factors in patients with only brain metastasis as the postoperative initial recurrence after resection of NSCLC

    Methods
    We conducted a retrospective study of patients who had undergone resection for NSCLC between 1992 and 2012 and found 113 had experienced postoperative brain metastasis as initial metastasis. We reviewed these patients retrospectively.

    Results
    The 1-year survival and 3-year survival rate after the diagnosis of brain metastasis was 39.8% and 19.0 %. On univariate analysis, the significant prognostic factors included gender (3-year survival rate, female versus male; 26.3% versus 15.6%, p = 0.027), pneumonectomy (3-year survival rate, pneumonectomy versus non-pneumonectomy; 5.6% versus 27.4%, p = 0.009), adenocarcinoma (3-year survival rate, adenocarcinoma versus non-adenocarcinoma; 10.7% versus 25.3%, p = 0.016) and interval to brain metastasis after surgery (3-year survival rate, < 1 year versus 1 ~2 year versus >2 year; 14.2% versus 25.3% versus 38.9%, p = 0.049).

    Conclusion
    In patients with brain metastasis after lung resection for NSLCL, female, non-pneumonectomy, non-adenocarcinoma and longer interval to metastasis after surgery showed favorable positive prognosis.