Author of

• 10643

  +

  P1.07 - Poster Session 1 - Surgery (ID 184)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/28/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 10648

    +

    P1.07-005 - Length of disease free survival interval is an independent predictive prognostic factor for postrecurrent survival in NSCLC (ID 860)

    09:30 - 09:30  |  Author(s): M. Kato
    • Abstract

    Background
    Lung cancer is still one of the deadly types of cancer. Once the disease has relapsed, long survival cannot be anticipated. However, prognostic factors after postoperative recurrence in non-small cell lung cancer (NSCLC) have not been well elucidated. In the present study, to improve the prognosis for NSCLC, we focused disease free survival (DFS) interval length and newly examined predictive survival factors after recurrence for NSCLC for over 10 years.

    Methods
    Consecutive 419 patients with NSCLC were performed curative surgical operation between January 2001 and March 2012 at the Department of Thoracic Surgery, Hamanomachi Hospital, Fukuoka, Japan. Out of 419 patients, 116 cases had been recurrent. Predictive prognostic factors for 116 recurrent NSCLC cases were retrospectively examined.

    Results
    DFS time which is longer than 18 months as well as female gender and adenocarcinoma histology were independent better prognostic factors for 116 recurrent patients. For 74 patients with adenocarcinoma, DFS time which is longer than 20 months as well as female gender, younger age and EGFR mutation status were independent better prognostic factors in multivariate analysis.

    Conclusion
    In the present study,we for the first time demonstrated that DFS time is an independent prognostic factor for recurrent NSCLC.We have also shown that female gender, younger age and adenocarcinoma histology were independent predictive prognostic factors for all cases. Among several prognostic factors, in this study, however, we emphasis DFS interval time as an independent prognostic factor for postrecurrent survival. The recurrent patients whose DFS time is shorter than 20 months should be taken care intensively.