Author of

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  P1.07 - Poster Session 1 - Surgery (ID 184)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/28/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

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    P1.07-002 - Effect of synchronous solitary bone metastasectomy on resectable non-small cell lung cancer patients (ID 169)

    09:30 - 09:30  |  Author(s): T. Zhao
    • Abstract

    Background
    Lung cancer is the most common cause of cancer related death among both men and women all over the world. Skeleton is one of the most common metastatic sites. Most of the patients with bone metastasis should be treated with systemic therapy or symptom-based palliative approach without surgery. We try to improve the therapeutic effect by synchronous surgeries in resectable non-small cell lung cancer(NSCLC) patients with solitary bone metastasis.

    Methods
    Five patients have undergone synchronous lung cancer resections and solitary bone metastasectomies between 2009 to 2011 in our hospital. All of them have received 18FDG-PET-CT or Bone Scintigraphy (BS) to demonstrate solitary bone metastasis and exclude other site metastases. They received standard lung cancer resections and mediastinal lymph node resections. Meanwhile, bone leasions were assessed by orthopedists and operated with standard procedures synchronously. After operations they all had standard chemotherapies. Perioperative indicators including time of thoracic drainage, hospital stays, incidence of postoperative complications and progress free survival (PFS) were observed.

    Results
    The average time of postoperative drainage is 4.6±1.1 days, postoperative hospitalization is 8.8±2.2 days. All of the procedures were carried out safely with no serious complications. The PFS of these patients is 13.2±7.7 months. Two patients with spine metastasis died about one year after operation, and the other three patients with limb bone metastases have survived more than 16 months in average after operation and still alive.Figure 1

    Conclusion
    Synchronous metastasectomy and lung tumor resection is safe to patients. The PFS time and survival results show that in the rare situation in which a patient has a solitary bone metastasis, aggressive surgical treatment may be an available choice.