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Y. Xu



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    P3.08 - Poster Session/ Thymoma, Mesothelioma and Other Thoracic Malignancies (ID 226)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Thymoma, Mesothelioma and Other Thoracic Malignancies
    • Presentations: 1
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      P3.08-025 - Clinical and Radiographic Manifestation of PPNHL in Chinese Patients: Differentiation of MALT Type and DLBCL Type (ID 771)

      09:30 - 09:30  |  Author(s): Y. Xu

      • Abstract
      • Slides

      Background:
      Primary pulmonary non-Hodgkin’s lymphoma (PPNHL) is a rare extranodal lymphoid neoplasm with few reports of Chinese patients. This study aims to analyze the demographic data, clinical features and radiographic presentation of Chinese PPNHL patients to obtain useful information for early diagnosis and differential diagnosis.

      Methods:
      A retrospective review of primary pulmonary non-Hodgkin’s lymphoma diagnosed at our hospital from February 2007 to April 2014 was performed.

      Results:
      This study included 34 PPNHL patients, comprising of 25 cases of mucosa-associated lymphoid tissue (MALT) lymphoma and 9 cases of diffuse large B-cell lymphomas (DLBCL). Cough and expectoration were the most common symptoms, accounting for 57.9% of the patients with symptoms. Nodules, masses and consolidations were the most frequent radiologic abnormalities and right lung is often involved. Pericardial effusion and bronchial abnormalities were found only in DLBCL cases. CT-guided percutaneous transthoracic biopsy was performed in most of the patients (73.5%) for diagnosis.

      Conclusion:
      The clinical features of PPNHL lack specificity. Imaging findings indicated that DLBCL patients tend to have an elevated incidence of pericardial effusion and bronchial abnormalities than MALT types. These discoveries provide assistance for the early diagnosis and differential diagnosis of these subtypes.

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