Author of

• 15530

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  P3.06 - Poster Session/ Screening and Early Detection (ID 220)

  • Event: WCLC 2015
  • Type: Poster
  • Track: Screening and Early Detection
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/09/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)

  • 15550

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    P3.06-020 - CT-Guided Percutaneous Fine Needle Biopsy for Small Lung Tumor (≤ 2cm) and Diffficult Pulmonary Lesions  (ID 2579)

    09:30 - 09:30  |  Author(s): X. Qiu
    • Abstract

    Background:
    lung cancer is increasing rapidly in China. There are more and more peripheral small lung cancer (≤2cm) was found. CT-guided percutaneous fine needle biopsy becomes first of choice for pathological diagnosis of peripheral small lung tumor (≤2cm) and some central pulmonary lesions which could not be pathologically diagnosed by fiberoptic bronchoscopy. We developed CT-guided percutaneous fine needle biopsy (CT-NB) for detecting early stage lung cancer (size ≤2cm peripheral small lung cancer) since 1992. We discuss typical cases here.
    
    Methods:
    Case1: Man, aged 52, right lower lobe 1.5cm ball tumor, no typical malignant sign; unwilling to undergo surgery due to years’ coronary heart disease; CT-NB was performed and lung adenocarcinoma was diagnosed. Case2: Man, aged 63, right upper lobe 1.2cm ball tumor, with cardiopulmonary dysfunction; CT-NB was performed and found some inflammatory cells, but no malignant tumor cells found. Case3: Man, aged 40, heavy smoker, cough and blood-tinged sputum for one month, left lower lobe 3.5cm irregular mass, regional and subcarinal lymph node swollen, clinically progressed rapidly, suspected small-cell lung cancer (SCLC), T2N2M0; at least pneumonectomy was needed if want resected; CT-NB was performed and non-small cell lung cancer (NSCLC) was diagnosed, and SCLC was excluded.
    
    Results:
    For Case 1: right lower lobe resection and lymph node dissection was performed, postoperative diagnosis was adeno-squamous cell carcinoma, 1.5X1.3X1.3cm, lymph node negative, pT1N0M0 Stage I, early stage lung cancer. He was alive healthily more than five years postoperatively. For Case 2: considered as a benign disease; carefully follow-up for more than 5 years, no malignant sign. For Case 3: left pneumonectomy and lymph node dissection was performed; postoperative diagnosis was squamous cell carcinoma; pulmonary ligament lymph node positive, others negative, pT2N2M0 StageIIIA; radiation followed. He was alive healthily more than five years postoperatively.
    
    Conclusion:
    CT-NB is a very useful diagnostic method for peripheral small lung tumor (≤2cm) and some central pulmonary lesions with fiberoptic bronchoscopy failed. CT-NB could be used to confirm the diagnosis of lung cancer, to help make decision for surgically resection, to help cure more early stage lung cancer patients, to help improve the prognosis of lung cancer treatment. CT-NB could also be used to exclude lung cancer diagnosis, to avoid unnecessary surgery, especially for those aged, cardiopulmonary dysfunction, high risk patients. CT-NB could be used to confirm the pathological type of lung cancer before treatment applied, to help distinguish SCLC from NSCLC, to help select the best choice of treatment modality of chemotherapy and radiation according to patient’s age, cardiopulmonary function status, pathological type, and gene types.