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H. Kawai
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P3.02 - Poster Session/ Treatment of Localized Disease – NSCLC (ID 211)
- Event: WCLC 2015
- Type: Poster
- Track: Treatment of Localized Disease - NSCLC
- Presentations: 1
- Moderators:
- Coordinates: 9/09/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)
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P3.02-026 - Positive or Negative Indications for Wedge Resection of Non-Small Cell Lung Cancer (ID 427)
09:30 - 09:30 | Author(s): H. Kawai
- Abstract
Background:
Limited resection for non-small cell lung cancer is gaining popularity because of early detection and the increase of elderly patients. To reveal the relevant indications for wedge resection, we retrospectively investigated patients who underwent wedge resection by dividing them into positive (PW) and negative (NW) indication groups.
Methods:
Clinical N0M0 cases with tumours <1 cm or predicted lepidic pattern adenocarcinoma were labelled PW, while other wedge resection cases were labelled NW. We investigated 35 PW and 32 NW cases surgically treated at our hospital between 2002 and 2009. The mean age was 66 years in the PW group and 77 years in the NW group. All PW cases were c-stage IA, while the NW group included 21, 7, 2, and 4 cases of IA, IB, IIB, and IIIB, respectively.
Results:
The overall 5-year survival rates (OS) of the PW and NW groups were 100% and 59.4%, while the disease-specific 5-year survival rates (DS) were 100% and 82.6%, respectively. The indications for (number of) limited resections in the NW group were low respiratory function (15), other malignancies (4), cardiac disease (4), cerebral disease (3), and other (5). The OS/DS of the NW group were 57.1/85.7 for IA; 71.4/100 for IB; 0/0 for IIB; and 50/50 for IIIB. There were 9 cases of death due to other diseases. There were 6 cases of death due to lung cancer recurrence. Among the patients with c-stage I tumours, 7 died of other disease, while only 2 died of lung cancer distant metastasis recurrence (Table). TableDeath due to lung cancer 6 Death due to other diseases 9 1st recurrence site Other malignancy 4 bone 3 Cardiovascular disease 2 pleura 2 Cerebral disease 1 brain 1 Liver failure 1 Hemorrhagic enteritis 1
Conclusion:
Wedge resection is positively indicated in PW cases. Negative wedge resection should be positively indicated in NW cases of c-stage I disease because treatment for other diseases must start as quickly as possible to maximize quality of life.
