Author of

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  P2.06 - Poster Session/ Screening and Early Detection (ID 219)

  • Event: WCLC 2015
  • Type: Poster
  • Track: Screening and Early Detection
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/08/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)

  • 14628

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    P2.06-016 - An Epidemiological Study on Detection of Chronic Obstructive Pulmonary Diseases and Lung Cancer by Regional Lung Cancer Mass Screening (ID 1164)

    09:30 - 09:30  |  Author(s): Y. Sekine
    • Abstract
    • Slides

    Background:
    Lung cancer is a major cause of death in the world and chronic obstructive pulmonary disease(COPD) are at risk for lung cancer. Both the diseases have common etiologies, including cigarette smoking. We aimed to clarify the effectiveness of lung cancer screening by chest X-ray and by low-dose computed tomography（LDCT）among patients with COPD tested by pulmonary function test(PFT) by using regional lung cancer mass screening.
    
    Methods:
    A total of 7,067 residents including 2,720 males and 4,347 females of Togane City, Chiba, Japan received lung cancer screening between May and July, 2011. All residents underwent chest X-ray and answered questionnaire, including smoking history , chronic respiratory symptoms and lifestyle-related disease for selecting COPD. We hypothesized that individuals with a positive smoking history with chronic respiratory symptoms or lifestyle-related disease considered COPD candidates and advised to undergo PFT. COPD candidates whose forced-expiratory volume in 1 second/ forced vital capacity less than 70 % were considered COPD who underwent LDCT. They were followed additional two years by high resolution CT for detecting lung cancer.
    
    Results:
    Chest X-ray showed normal in 6,749 and abnormal in 318(4.5%). Among participants with normal chest x-ray, positive COPD candidates were 1,686(23.9%) and negative COPD candidates were 5,381(76.1%), according to the questionnaire. 1,500 of 1,686 underwent PFT and diagnosed COPD in 171(2.4%). 151(2.1%) of them received LDCT. Six of 318(1.9%) cases with abnormal chest X-ray were finally diagnosed lung cancer (86/100,000). One case at initial time and three cases during follow-up periods were diagnosed lung cancer by LDCT in COPD patients (0.88 % per year).
    
    Conclusion:
    Chest X-ray and LDCT for COPD patients may be effective for lung cancer surveillance in community-based lung cancer screening.
    
    

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