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M.I. Patel



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    P1.04 - Poster Session/ Biology, Pathology, and Molecular Testing (ID 233)

    • Event: WCLC 2015
    • Type: Poster
    • Track: Biology, Pathology, and Molecular Testing
    • Presentations: 1
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      P1.04-025 - Lung Cancer Incidence by Histology, Gender, Race/Ethnicity and Socioeconomic Status (ID 266)

      09:30 - 09:30  |  Author(s): M.I. Patel

      • Abstract
      • Slides

      Background:
      The incidence trends of lung cancer (LC) by histology, gender, race/ethnicity and neighborhood socioeconomic status (nSES, derived from US Census data) have not been reported. To examine these trends, we conducted a population-based study, using data from the California Cancer Registry across three discrete time periods to correspond with Census data on nSES: 1988-1992; 1998-2002; 2008-2011.

      Methods:
      Incidence data for invasive LC were abstracted for the three time periods. In each time period, male and female age adjusted incidence rates of LC and incidence rate ratios were calculated by histologic cell type and stratified by nSES.

      Results:
      A total of 240,307 LC cases were identified across the three time periods. Histology incidence trends by race/ethnicity are shown in Figure 1 and by nSES in Table 1 for males and females. Larger declines in incidence were seen over the 3 time periods among males than females. Among males, incidence rate declines over time were seen in all race/ethnic and nSES groups, but were largest among Blacks and Hispanics. Across all races/ethnicities among males, there was a slight increase over time in the incidence of adenocarcinoma histology. Among females, incidence rate declines were seen among Hispanics regardless of nSES, mid- and high-nSES Whites, and low- and mid-nSES Blacks; incidence trends among Asian/Pacific Islander females did not change significantly over time, regardless of nSES. Among females, there were variations in incidence trends by histology with a slight increase in the adenocarcinoma histology. Figure 1Figure 2





      Conclusion:
      Our findings demonstrate differences in LC incidence over time by histology, gender, race/ethnicity and SES. While incidence rates consistently declined for males, there were greater declines in incidence for the high SES patient populations. For females, there were variations in trends by histology, race/ethnicity, and SES. These findings warrant further investigation.

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