Author of

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  P3.24 - Poster Session 3 - Supportive Care (ID 160)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Supportive Care
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/30/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 12855

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    P3.24-002 - Incidence of Lung Entrapment in Malignant Pleural Effusion (ID 105)

    09:30 - 09:30  |  Author(s): I. Bin Mohamed Noor
    • Abstract

    Background
    Malignant pleural effusion s occur in up to 15% of patients with advance malignancies. However, the incidence of lung entrapment in patients with malignant pleural effusions has never been reported. This may have an impact in the management of patients with malignant pleural effusions, as pleurodesis is unlikely to suceed. A two year review of patients with malignant pleural effusions who underwent medical pleuroscopy was perform, looking at the incidence of lung entrapment. Medical pleuroscopy has been performed in our hospital since January 2011.

    Methods
    A review of the records of patient who underwent medical pleuroscopy from 1 January 2011 to 31 December 2012 was performed. Patients with histology proven malignant effusions were included in our analysis. The incidence of lung entrapment was recorded based on the procedure report entered by the performing physician.

    Results
    Over a two year period, seventy-three medical pleuroscopies were performed. All patients underwent pleuroscopy guided parietal pleura biopsies. Out of 73 cases, thirty six (49.3%) were confirmed malignant on histology. Of the cases with histology proven malignant effusion, there were twenty five cases of primary lung cancer (69.4%), 10 cases of primary breast cancer (27.8%) and one case of primary cervical cancer (2.8%). Adenocarcinoma was the histology in 96% of patients with metastatic lung cancer (twenty four out of 25 patients) . The remaining patient patient with metastatic lung cancer was found to have squamous cell carcinoma. The incidence of lung entrapment among patients with histology proven malignant pleural effusion who had undergone pleuroscopy in our study was 94.4% (thirtyy four of 36 patients). Entrapment was not seen in two cases of metastatic lung adenocarcinoma.

    Conclusion
    Our study shows a 94.4% incidence of lung entrapment in patients with malignant pleural effusion who had undergone medical pleuroscopy. However, more studies are needed to look at the incidence of lung entrapment, as not all patients are fit to undergo medical pleuroscopy. Furthermore, pleuroscopy is not readily available in most hospitals world wide. If the overall incidence is indeed high, the long term management of malignant plerual effusions will require a review, in particular, the use of talc in pleurodesis.