Author of

• 12837

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  P3.22 - Poster Session 3 - Epidemiology, Etiology (ID 168)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Prevention & Epidemiology
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/30/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 12846

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    P3.22-009 - Lung cancer in women: clinical and pathologic features (ID 3388)

    09:30 - 09:30  |  Author(s): A. Tomruk
    • Abstract

    Background
    There is scientific evidence of increasing lung cancer incidence in women. and lung cancer pattern and risk factors in women are not the same as with men due to genetic and hormonal differences

    Methods
    In this study we reviewed the clinical and pathologic features in our female lung cancer patients diagnosed and followed at our clinic between 2005 and 2009.

    Results
    In this period, we followed 360 lung cancer patientsl. Of them, 30(8.3%) were women.Their mean age was 62.83 +/- 12.43 (range 33-83). 93.4% (n:28) were housewives, 80% (n:24) were nonsmoker, 13.3%(n:4) were exsmoker, 6.7% (n:2) were current smokers. 93.7'% were postmenapausal women. They had no history of cancer, COPD, asthma, or tuberculosis. Hypertension, coronary arterial disease, and DM were present in 20% (n:6), 10% (n:3), and 6.6% (n:2) of them respectively. Only one patient (3.3%) was aymptomatic. Most common symptoms were cough, dyspnea, chest pain and hemoptysis in order. At the time of diagnosis, 63.3%(n:19) were ECOG 0, 23.3% (n:7) were ECOG 1, 13.3% (n:4) were ECOG 2. Histopathologic diagnosis were adenocarcinoma in 53.3%, squamous cell carcinoma in 13.3%, NSCLC (not otherwise specified) in 16.7% and SCLC in 16.7%. Of NSCLC patients only 8.6% were early stage, remaining 91.4% were locally advanced or metastatic disease. 20% of SCLC patients were at limited stage, remaining 80% had extensive disease. Most common sites of metastasis were lung/pleura (40%), brain (36.7%) and bone(30%). Three patients rejected any form of therapy. Surgery +/- adjuvant therapy were applied to 2 patients, chemotherapy +/- radiotherapy were given to 22 patients.

    Conclusion
    In conclusion, majority of our women lung cancer patients were nonsmokers, with adenocarcinoma histology, postmenapausal and in good performance status.