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K. Kosanam Subramaniam



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    P2.24 - Poster Session 2 - Supportive Care (ID 157)

    • Event: WCLC 2013
    • Type: Poster Session
    • Track: Supportive Care
    • Presentations: 1
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      P2.24-019 - Pleurodesis with bleomycin in advanced non small cell lung cancer: A single centre experience from Southern India (ID 1319)

      09:30 - 09:30  |  Author(s): K. Kosanam Subramaniam

      • Abstract

      Background
      Pleurodesis is an accepted therapy for patients with recurrent and massive pleural effusion in patients with advanced non small cell lung cancer.Bleomycin is safe and effective for chemical pleurodesis in several studies.The aim of this study was to study the effectiveness of bleomycin pleurodesis in advanced non small cell lung cancer.

      Methods
      Seventy five cases of proven non small cell lung cancer ; with recurrent and symptomatic pleural effusion admitted to our hospital between 2006 - 2012 were included in the study. All patients received chemical pleurodesis with 60 units of bleomycin after pleurocentesis using intercostals drainage.All patients received systemic chemotherapy following pleurodesis.

      Results
      The clinical control of pleural effusion by 4 weeks of procedure and the need for a repeat pleurodesis was analysed.The success rate was 76.7 per cent (95% CI,68.6 – 88.7 %). The only significant complication reported was chest pain of varying degrees. There were no deaths associated with bleomycin pleurodesis.

      Conclusion
      Bleomycin pleurodesis may be considered as safe and cost effective treatment in patients with advanced non small cell lung cancer with symptomatic pleural effusion in developing countries.