Author of

• 11595

  +

  P2.07 - Poster Session 2 - Surgery (ID 190)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/29/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 11641

    +

    P2.07-046 - Effect of airway stenting on quality of life (QoL) in patients with malignant airway obstruction: A single institutional experience at Mayo Clinic Arizona (MCA) (ID 3203)

    09:30 - 09:30  |  Author(s): A.C. Dueck
    • Abstract

    Background
    Malignant airway obstruction is associated with severe respiratory distress and poor outcome. Airway stents have been used to relieve malignant airway obstruction and may provide significant palliation of symptoms, but quality of life data after airway stenting is lacking. We report the Mayo Clinic Arizona experience with the Boston Scientific Ultra Flex stent in the management of malignant airway obstruction.

    Methods
    A single center study evaluating quality of life before and after placement of the Boston Scientific Ultra Flex stent for malignant airway obstruction. Quality of life data (SF-36 questionnaires) before and after stent placement were obtained prospectively. Charts were reviewed retrospectively. Patients were enrolled from 2007-2011 at Mayo Clinic Arizona. The study was approved by the Mayo Foundation IRB. Informed consent was obtained and documented in the clinical record. SF-36 questionnaires were completed by the patients in the outpatient clinic before (baseline) and after stent placement.

    Results
    From 2007 to 2011, 19 patients underwent placement of Boston Scientific Ultraflex non covered tracheobronchial stents for airway obstruction. 3 of the 19 patients underwent stent placement for benign etiologies and were excluded from the analysis. Of the remaining 16 patients, 8 were male and 8 were female. The median age was 64.5 years. Non-small cell lung cancer was the most common underlying diagnosis (11 patients). The remaining patients had head and neck cancer (2 patients), esophageal cancer (1 patient), metastatic Hurthle cell thyroid cancer (1 patient) and metastatic renal cell carcinoma (1 patient). The most common presenting symptom of airway obstruction was dyspnea. Data from SF36 forms were available in 8 of 16 patients. There was a significant improvement in the physical component score (PCS) (10.4±10.1, P=0.02), and a non-significant improvement in the mental component score (MCS) (1.4±6.2, P=0.54) after stent placement.

    Conclusion
    Placement of airway stents for malignant bronchial obstruction resulted in significant palliation of symptoms and improvement in patient quality of life.