Author of

• 11595

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  P2.07 - Poster Session 2 - Surgery (ID 190)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/29/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 11617

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    P2.07-022 - Prognostic Implication of Cytodiagnosis of Minute Pleural Effusion found at Thoracotomy in NSCLC Patients (ID 1788)

    09:30 - 09:30  |  Author(s): T. Toyoda
    • Abstract

    Background
    In order to clarify clinical implication and therapeutic strategies managing minute malignant pleural effusion unexpectedly found at thoracotomy, we analyzed diagnostic results of cytodiagnosis of pleural effusion found at thoracotomy and prognosis of the patients treated in our institute retrospectively.

    Methods
    From 2004 to 2013, 502 non-small cell lung cancer patients were surgically treated in our institute. At the time of thoracotomy pleural effusion cytology (PEC) was performed in the cases that small amount of subclinical, minute pleural effusion was found unexpectedly. In some cases pleural lavage cytology (PLC) was performed simultaneously.

    Results
    In 254 patients (50.6%) out of 502, minute pleural effusion was detected and PEC was performed. In 25 patients (9.8%), malignant pleural effusion was demonstrated. PLC was performed in 191 cases, and positive results were obtained in 16 cases (8.3%). In these 16 cases, PEC was also performed in 12 cases and positive results were obtained in 11 cases. And in 4 cases no pleural effusion was found but PLC was positive for malignancy. Post operative 5 yrs survival of malignant pleural effusion group was 43.7%. In p-N0 cases, post operative survival of PEC positive cases was tend to poorer than surgically treated PEC negative cases (p=0.13), but in p-N1, N2 cases, post operative survival was almost equal between these groups (p=0.66).

    Conclusion
    Cytodiagnosis of minute pleural effusion found at thoracotomy was performed in 51% of surgical cases of NSCLC. Subclinical malignant pleural effusion found at thoracotomy may be a prognostic factor in clinical stage one case. PLC at the time of thoracotomy may become a complementary examination of PEC.