Author of

• 11595

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  P2.07 - Poster Session 2 - Surgery (ID 190)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/29/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 11612

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    P2.07-017 - Pulmonary Resection for Lung Cancer Patients with Cerebrovascular and Cardiovascular Comorbidities (ID 1509)

    09:30 - 09:30  |  Author(s): N. Izumi
    • Abstract

    Background
    Patients with cerebro- and cardio-vascular comorbidities (CCVC) who undergo surgery represent a high-risk group and require careful perioperative management. In the present study, we aimed to retrospectively analyze the postoperative complications (POC) of patients with CCVC who had undergone pulmonary resection for lung cancer. Patients with cerebro- and cardio-vascular comorbidities (CCVC) who undergo surgery represent a high-risk group and require careful perioperative management. In the present study, we aimed to retrospectively analyze the postoperative complications (POC) of patients with CCVC who had undergone pulmonary resection for lung cancer.

    Methods
    Among 288 patients who underwent pulmonary resection at our institution from January 2009 to December 2011, we examined the records of 51 patients with CCVC (17.7%) to identify the risk factors for developing POC. Among the analyzed patients, we noted the presence of 34 POC, including tachyarrhythmia in 9, prolonged pulmonary fistula in 9, pyothorax in 2, cerebral infarction in 2, requirement of long-term oxygen therapy in 2, interstitial pneumonia in 2, delirium in 2, and other POC in 4. Several patients had multiple POC.

    Results
    We examined 43 male patients (84.3%); the median age was 72 years and the median preoperative forced expired volume in 1s (FEV~1~) was 2200 mL (range, 1120–3420). The patients with CCVC included 12 with cerebral infarction, 2 with transient cerebral ischemic attacks, 2 with cerebral hemorrhage, 1 with subarachnoid hemorrhage, 4 with cerebral aneurysm, 10 with arrhythmia, 17 with ischemic heart disease, 1 with valvular heart disease, 8 with aortic aneurysm/dissection, 11 with peripheral arterial disease, and 1 with a left atrial myxoma; several of these patients had multiple CCVC. Moreover, 2 patients underwent pneumonectomy, 37 underwent lobectomy, 3 underwent segmentectomy, and 9 underwent wedge resection. Postoperative morbidity rates were 21.4% in cerebrovascular comorbidity patients (p = 0.015), 53.5% in the cardiovascular comorbidity patients (p < 0.0001), 71.4% in CCVC patients (p = 0.0028), and 12.3% in patients without CCVC. No operative or in-hospital mortality was noted. Gender, age, smoking status, and smoking index were not found to be significantly related to the incidence of POC. However, patients with an FEV~1~ < 2200 mL were found to be significantly more likely to develop POC (p = 0.036).

    Conclusion
    We noted that patients with CCVC and low FEV~1 ~were more likely to develop POC.