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Y. Shen-Tu



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    P2.07 - Poster Session 2 - Surgery (ID 190)

    • Event: WCLC 2013
    • Type: Poster Session
    • Track: Surgery
    • Presentations: 1
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      P2.07-005 - A comparative study of diagnosing and staging by mediastinoscopy or EBUS on lung cancer (ID 737)

      09:30 - 09:30  |  Author(s): Y. Shen-Tu

      • Abstract

      Background
      Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS) has been gradually application in clinic, but its value in staging of lung cancer and dignosing of mediastinal mass need to be evaluated. We intends to study comparatively the clinical value of EBUS and mediastinoscopy, and, want to provide a basis for the rational choice applications.

      Methods
      Between July 2009 and December 2012, 361 patients accepted mediastinoscopy, including 199 cases of lung cancer and 162 of mediastinal mass. During the same period, 348 patients accepted EBUS , including 216 cases of lung cancer and 132 of mediastinal mass. All of the biopsy samples were tested in the pathological department of Shanghai chest hospital. Analyzing the data of two groups and comparing the clinical value of mediastinoscopy and EBUS both on preoperative staging of lung cancer and diagnosing of mediastinal mass.

      Results
      With the pathological results as a gold diagnosis standard, the accuracy, sensitivity and specificity of mediastinoscopy diagnostic efficacy are 98.28%, 98.03% and 100%, respectively on lung cancer, and, 98.11%, 97.62% and 100%, respectively on mediastinal mass. For EBUS, the accuracy, sensitivity and specificity of diagnostic efficacy are 95.69%, 94.74% and 100%, respectively on lung cancer, and, 82.64%, 77.42% and 100%, respectively on mediastinal mass. Two techniques have not significant difference on diagnosing and staging of lung cancer (P>0.05), but have statistically difference on mediastinal mass (P<0.05), especially on sarcoidosis (P=0.0109), tuberculosis(P=0.0135) and lymphoma(P=0.0036).

      Conclusion
      Mediastinoscopy and EBUS have a similar clinical value in diagnosing and staging on lung cancer, but mediastinoscopy is superior to EBUS in diagnosing on mediastinal mass.

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    P3.07 - Poster Session 3 - Surgery (ID 193)

    • Event: WCLC 2013
    • Type: Poster Session
    • Track: Surgery
    • Presentations: 1
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      P3.07-009 - Combined use of virtual puncture by simulator with methylene blue stain localization of the pulmonary peripheral nodules (ID 735)

      09:30 - 09:30  |  Author(s): Y. Shen-Tu

      • Abstract

      Background
      To explore the new technique of combined use of virtual puncture by simulator with methylene blue stain localization of the pulmonary peripheral nodules. And, evaluate the efficacy on focus localization and the clinical useful value of this method. To explore the new technique of combined use of virtual puncture by simulator with methylene blue stain localization of the pulmonary peripheral nodules. And, evaluate the efficacy on focus localization and the clinical useful value of this method.

      Methods
      During July 2011 to February 2013, total 80 pulmonary peripheral nodules of 75 patients were virtually punctured before operation. The methylene blue injected after anesthesia according to the identified skin point, angle and depth of preoperative virtual puncture. Then, marked lung tissue wedge resected under VATS. The samples were examined by pathologist during operation. The proper surgical style was decided to the pathological results. All of the data, including focus diameter, distance of colored spot and the lesions, localization time, interval time from injection finished to stain spot observed , successful localization and complication rate, were recorded and analyzed.

      Results
      75 of 80 pulmonary peripheral noudles were successfully localized. The accuracy rate of localization is 92.65%. Forty two nodules were primary lung cancer, those patients were accepted the lobectomy and systematic lymph node dissection. Twenty five nodules were benign lesion, one was metastatic tumor. Focus diameter was 10.15±3.57mm, distance of stain spot and the lesions was 5.54±2.83mm, localization time was 22.44±5.19min, interval time of injection finished to stain spot observed was 16.93±2.17min. All cases had no complication.

      Conclusion
      The new technique, combined preoperative virtual puncture by simulator with methylene blue stain localization of the pulmonary peripheral nodules, has high accuracy rate and safety. It is useful to localize the pulmonary peripheral nodules, especially for the early stage lung cancer lesion which hard to be seen or palpated during VATS.