Author of

• 10984

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  P1.22 - Poster Session 1 - Epidemiology, Etiology (ID 166)

  • Event: WCLC 2013
  • Type: Poster Session
  • Track: Prevention & Epidemiology
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/28/2013, 09:30 - 16:30, Exhibit Hall, Ground Level

  • 10985

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    P1.22-001 - An Nickel Workers Cohort Study in China (Jinchuan Cohort)-the Largest Nickel Population in World (ID 95)

    09:30 - 09:30  |  Author(s): T. Zheng
    • Abstract

    Background
    Nickel is one of the most widely distributed and used metals in the world. Exposure to nickel compounds can result in a variety of adverse effects on human health. The China Nickel Workers Cohort Study (Jinchuan cohort) is estimated to include more than 50 000 nickel workers.

    Methods
    Since 2011, all staff and workers have been eligible for a medical examination every 2 years, and these workers who participated in the medical examination will be in-person interviewed with a standardized and structured questionnaire with trained interviewers and will be included in the Jinchuan cohort study. The medical examination includes a comprehensive physical examination, biochemical examination, epidemiologic survey and collection of biological samples. The Jinchuan cohort has the largest data set from a cohort of nickel exposed workers with both questionnaire and laboratory-based information and the exposure and disease information will be updated every 2 years through the biannual survey and medical examination.

    Results
    The comprehensive epidemiological and biological data will permit the evaluation of a number of hypotheses concerning the health effects of nickel exposure. The unique repository of blood samples including blood cell, plasma, and serum collected at the time the epidemiology survey will provide a population-based platform to examine biological indicators that closely correlate with nickel exposure and illness by using molecular epidemiologic methods. All of the cryopreserved blood samples are being stored in cryogenic tubes for future studies.

    Conclusion
    We are conducting the first occupational epidemiological study of nickel exposure in China among over 50 000 workers Comprehensive physical and biochemical examinations, an epidemiologic survey, and collection of biologic samples from workers are being used to evaluate the relationship between nickel exposure, cancer, and other health outcomes The cohort will be followed every two years with a repeat medical examination to update exposure and outcome information